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About the Investigational Study Therapy

What is the investigational study therapy?

The investigational study therapy, called TG-C, is a type of cell therapy, which has a mixture of human chondrocyte cells and transduced GP2-293 cells,  that are injected into the knee. The intended goal of this investigational cell therapy is to reduce knee pain and improve function.

The study therapy will be given as an injection. A medical professional will carefully insert a needle into your knee using an imaging device to help guide them.

Will I receive the study therapy?

Participants will be randomized at a 2:1 ratio, where:

What is an “investigational medicine?”

Investigational means the study medication is not approved by regulatory authorities like the US Food and Drug Administration (FDA), and it can only be used in clinical research studies like the ACTIVION-II study.